Carbon-carbon (C–C) bond formation is a fundamental transformation of synthetic organic chemistry. The ability to elaborate and extend a carbon framework via a series of C–C bond-forming reactions is paramount to medicinal chemistry, agrochemical synthesis, and natural product synthesis.

Tremendous advances have been made in the synthetic methods available for C–C bond formation due to the development of robust and reliable protocols for cross-coupling, increased accessibility to various organometallic reagents, and the creation and improvement of stoichiometric reagents which serve to place a specific carbon-containing moiety.

We have a wide breadth of powerful C–C bond-forming reagents. Our phosphonium salts are used in Wittig reactions, and phosphonates are employed in Horner-Wadsworth-Emmons (HWE) reactions to create various alkene-containing products. We have a diverse selection of reagents for trifluoromethylation and difluoromethylation, many of which can be employed under mild conditions and have broad substrate scopes. Our extensive array of palladium, ruthenium, and other metal precatalysts and catalysts are optimal for various cross-coupling reactions. Additional carbon-carbon bond-forming reagents include boronic acids and derivatives, alkynes, triflates, and halogenated substrates. In addition, we have various catalysts for olefin and alkyne metathesis available for your research.

Trigger your organic reactions with our carbon-carbon bond-forming reagents to reach your new frontiers.