Solid phase microextraction (SPME) is an innovative and sensitive solvent-free sample preparation technology. Based on the principle of adsorption/absorption and desorption, SPME uses a coated fiber to concentrate volatile and semi-volatile compounds from a sample.

SPME is widely used for a variety of applications involving environmental, biological and pharmaceutical samples, foods and beverages, flavors and fragrances, forensics and toxicology and product testing. Typical uses include: